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Article printed in the Arizona Republic on Tuesday, January 13, 2004
This article is provided for your information and use.

Vitamin D might cut risk of MS, study says

Study focuses on theory lack of sunlight may be main cause of disease
Milwaukee Journal Sentinel

MILWAUKEE - A huge study testing a long-held theory about the cause of multiple sclerosis has found that women who took a Vitamin D supplement cut their risk of developing the incurable neurological disorder by 40 percent, compared with those who did not take the supplement.

The study, which involved 187,563 women, is the first large, prospective examination of an observation that has been around for decades - that MS might be caused in part, by a lack of sunlight sufficient to allow the body to make its own Vitamin D.

The finding has particular relevance to people in Wisconsin and other Northern states where the incidence of MS is substantially higher.

In about the northern half of the United States, the incidence of MS is 110 to 140 cases per 100,000, compared with 60 to 80 cases per 100,000 in the southern half. And in areas near the equator, the rate of MS is very low.

"We found that it is (Vitamin D) protective against MS," said Kassandra Munger, the study's lead author and a researcher in the Department of Nutrition at the Harvard School of Public Health. "How long that protection lasts, I'm not sure."

Multiple sclerosis is a chronic, lifetime disease that is diagnosed mainly in young adults, according to the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, which funded the study.

In the United States, as many as 350,000 people have the disease.

MS is caused by an inflammation of nerve fibers in the central nervous system, which in turn, results in the destruction of myelin, a substance that insulates nerve fibers in the the brain and spinal cord.

Symptoms can vary in severity and may include vision problems, muscle weakness, a lack of coordination and balance, a feeling of "pins and needles" and numbness, and mild cognitive problems.

the disease is twice as common in women as men and also is more common in Caucasians than in other races.

Most people with MS have a normal life expectancy.

The study, appearing in the January issue of the Journal Neurology, is part of the ongoing Nurses' Health Study. The women in this study were followed for 10 to 20 years.

Those who took a daily multiple vitamin supplement with at least 400 international units of Vitamin D had 40 percent less incidence of MS than those who did not take a supplement with Vitamin D.

Depending on a person's age, 200 to 600 international units a day is recommended.

Vitamin D also is made in skin cells, which interact with sunlight. But with aging, a person's ability to make Vitamin D is reduced.

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